Thawj yam uas cuam tshuam rau kev tuav dej hauvHydroxypropyl methylcellulose yog siv(HPMC)cov khoom yog qhov degree ntawm kev hloov pauv (DS).DS hais txog tus naj npawb ntawm hydroxypropyl thiab methyl pawg txuas rau txhua chav cellulose.Feem ntau, qhov siab dua DS, qhov zoo dua cov dej tuav cov khoom ntawm HPMC.Qhov no yog vim qhov nce DS ua rau ntau pawg hydrophilic ntawm cov pob txha cellulose, tso cai rau kev sib cuam tshuam nrog dej molecules thiab txhim kho cov dej tuav.
Lwm qhov tseem ceeb cuam tshuam rau kev tuav dej yog qhov hnyav molecular ntawm HPMC.Molecular hnyav cuam tshuam rau viscosity ntawm HPMC cov kev daws teeb meem, thiab siab dua molecular hnyav polymers feem ntau pom cov dej tuav tau zoo dua.Qhov loj dua ntawm cov polymers no tsim cov qauv sib txuas ntau dua, ua rau muaj kev cuam tshuam nrog cov dej molecules thiab ua rau kev txhim kho dej tuav.Txawm li cas los xij, nws yog ib qho tseem ceeb kom nrhiav tau qhov sib npaug, vim tias qhov hnyav molecular ntau dhau tuaj yeem ua rau muaj viscosity thiab ua haujlwm tsis zoo, ua rau nws nyuaj rau kev tswj lossis siv HPMC cov khoom hauv qee yam kev siv.
Tsis tas li ntawd, qhov concentration ntawm HPMC nyob rau hauv ib tug formulation kuj plays lub luag hauj lwm tseem ceeb hauv kev tuav dej.Qhov siab dua ntawm HPMC feem ntau ua rau cov dej tuav tau zoo dua.Qhov no yog vim tias qhov concentration ntau dua ua rau muaj qhov chaw hydrophilic muaj rau kev nqus dej, ua rau muaj peev xwm tuav tau dej.Txawm li cas los xij, kev siv ntau dhau tuaj yeem ua rau muaj viscosity ntau ntxiv, ua rau cov txheej txheem nyuaj dua thiab siv tau.Nws yog ib qho tseem ceeb kom nrhiav tau qhov zoo tshaj plaws concentration ntawm HPMC raws li daim ntawv thov tshwj xeeb kom ua tiav cov dej tuav cov khoom uas xav tau yam tsis muaj kev cuam tshuam rau kev ua haujlwm ntawm cov khoom.
Ntxiv nrog rau cov ntsiab lus tseem ceeb no, ntau yam tseem ceeb tuaj yeem cuam tshuam cov dej tuav cov khoom ntawmHPMCcov khoom.Hom thiab tus nqi ntawm cov additives siv nyob rau hauv formulation tuaj yeem muaj kev cuam tshuam loj heev.Piv txwv li, qhov sib ntxiv ntawm plasticizers lossis rheology modifiers tuaj yeem txhim kho cov dej tuav los ntawm kev hloov pauv HPMC qhov kev sib haum xeeb thiab kev cuam tshuam nrog cov dej molecules.Ib puag ncig yam xws li kub thiab av noo tuaj yeem cuam tshuam cov dej tuav, vim tias cov kev txwv no cuam tshuam rau tus nqi ntawm cov dej evaporation thiab nqus.Lub substrate lossis cov khoom saum npoo tuaj yeem cuam tshuam ntxiv rau kev tuav dej, vim qhov sib txawv ntawm qhov porosity lossis hydrophilicity tuaj yeem cuam tshuam rau lub peev xwm ntawm substrate kom nqus thiab khaws dej.
Cov dej tuav cov khoom ntawm HPMC cov khoom raug cuam tshuam los ntawm ntau yam, suav nrog qib kev hloov pauv, qhov hnyav molecular, concentration, additives, ib puag ncig yam, thiab cov khoom siv substrate.Kev nkag siab txog cov xwm txheej no yog qhov tseem ceeb hauv kev tsimCov khoom siv raws li HPMCrau kev siv sib txawv.Los ntawm kev ua kom zoo rau cov xwm txheej no, cov tuam txhab lag luam tuaj yeem txhim kho cov dej khaws cia ntawm HPMC thiab ua kom nws cov txiaj ntsig zoo hauv kev lag luam xws li tshuaj, kev tsim kho, thiab kev saib xyuas tus kheej.Kev tshawb fawb ntxiv thiab kev txhim kho hauv daim teb no yuav txuas ntxiv nthuav peb txoj kev nkag siab ntawm cov yam ntxwv cuam tshuam rau kev tuav dej hauv HPMC cov khoom lag luam thiab ua kom muaj kev txhim kho ntawm cov qauv tsim tau zoo thiab muaj txiaj ntsig.
Post lub sij hawm: Nov-02-2023